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Interface Oral Health Science 2014 - Keiichi Sasaki

Year 2015


Part I Symposium I: Biosis–Abiosis Interface of Dental ImplantsChapter 1 Biological Events Occuring on the Biosis– Abiosis Interface: Cellular Responses Induced by Implantable Electrospun Nanofibrous Scaffolds1.1 Electrospun Nanofibrous Scaffolds as Implantable Biomedical Devices1.1.1 Categories of Electrospun Nanofibrous Scaffolds: Classified by Chemical Components1.1.2 Categories of Electrospun Nanofibrous Scaffolds: Classified by Electrospinning Techniques1.1.3 Biofunctionalization of Nanofibrous Scaffolds1.2 Cellular Responses Influenced by Electrospun Nanofibrous Scaffolds1.2.1 Biological Events Occuring on the Biosis–Abiosis Interface: The Role of Chemical Cues1.2.2 Biological Events Occuring on the Biosis–Abiosis Interface: The Role of Topographical Features1.3 Future ProspectiveChapter 2 Updates in Treatment Modalities and Techniques on Compromised Alveolar Ridge Augmentation for Successful Dental Implant Therapy2.1 Treatment Modalities for Augmentation of the Compromised Alveolar Ridge2.2 Autogenous Block Bone Grafting2.2.1 Autogenous Bone Donor Sites2.2.2 Block Bone Grafting Techniques2.2.3 The Fate of Autogenous Onlay Bone Graft2.2.4 Drawbacks of Autogenous Bone Grafting2.3 Biomaterials for Guided Bone Regeneration2.3.1 Bone Graft Materials2.3.2 Bioengineering Techniques2.4 Alveolar Ridge Augmentation by Distraction Osteogenesis2.4.1 Distraction Techniques2.4.2 Possible Amount of Bone Gain: Clinical Outcome2.4.3 Consolidation Enhancement FactorsChapter 3 Surface Modification of Dental Implant Improves Implant–Tissue Interface3.1 Dental Implant–Tissue Interface3.2 Effect of the Surface Geometry3.3 Control of Surface Chemistry3.4 Protein Application3.5 Application of Motif-Programming3.6 Plasma Treatment of Implant Surface3.7 Calcium Phosphate (Ca-P) Coating by Plasma Spraying3.8 Thin Ca-P Coatings3.9 Future of Dental ImplantChapter 4 Oral Microbiota in Crevices Around Dental Implants: Profiling of Oral Biofilm4.1 Introduction4.1.1 Quantitative and Qualitative Analyses of Oral Biofilm4.1.2 Oral Ecology: Environmental Factors Affecting Oral Biofilm4.2 Nutritional and Environmental Aspects of Dental Implants4.2.1 Fluid Volume4.2.2 Fluid Constituents4.2.3 Environmental Condition: Fluid pH4.3 Microbiota Around Implants4.3.1 Quantitative and Qualitative Analysis of Microbiota in PICF4.3.2 Metagenome (Pyrosequencing) Analysis of Microbiota in PICFPart II Symposium II: Biomaterials in Interface ScienceChapter 5 Biofunctionalization of Metallic Materials: Creation of Biosis–Abiosis Intelligent Interface5.1 Introduction5.2 Biosis–Abiosis Intelligent Interface5.3 Osseointegration of Titanium5.4 Mechanism of Osseointegration in Titanium5.5 Nanometer-Level Interface Structure5.6 Surface Treatment5.6.1 Change of Research Trend5.6.2 Surface Treatment5.6.3 Surface Treatment for Bone Formation5.6.4 Evolution of Surface Treatment for Bone Formation5.7 ConclusionsChapter 6 Evaluation of Photocatalytic Activity of the TiO2 Layer Formed on Ti by Thermal Oxidation6.1 Introduction6.2 TiO2 Layers on Ti and Ti Alloys for Biomedical Applications6.3 Preparation of Anatase-Rich TiO2 Layer on Ti and Ti Alloys6.4 Evaluation of Photocatalytic Activity of TiO2 Layers Formed by Two-Step Thermal Oxidation6.5 SummaryChapter 7 Enhancing Functionalities of Metallic Materials by Controlling Phase Stability for Use in Orthopedic Implants7.1 Introduction7.2 Low Young's Modulus7.3 Wear Properties of Low Young's Modulus Titanium Alloy7.4 Self-Tunable Young's Modulus7.5 Low Magnetic Susceptibility7.6 SummaryChapter 8 Surface Improvement for Biocompatibility of Ti-6Al-4V by Dealloying in Metallic Melt8.1 Introduction8.2 Dealloying in a Metallic Melt8.3 Surface Improvement of Ti-6Al-4V Alloy by Dealloying with a Metallic Melt [14]8.3.1 Morphology and Composition Change by Dealloying8.3.2 Effect of Crucible Material on Ion Release of Dealloyed Ti-6Al-4V8.4 SummaryChapter 9 Chemical Vapor Deposition of Ca–P–O Film Coating9.1 Introduction9.2 Chemical Vapor Deposition (CVD)9.3 CVD of Ca–P–O Films and Their Bio-Characteristics9.4 SummaryPart III Symposium: Biomedical Engineering InterfaceChapter 10 Importance of Visual Cues in Hearing Restoration by Auditory Prosthesis10.1 Introduction10.2 Recruitment of Visual Cues in Degraded Speech Conditions10.3 Auditory Training with Bimodal Audio-Visual Stimuli10.4 SummaryPart IV Symposium: Cell Manipulation and Tissue RegenerationChapter 11 Designer Supersurfaces via Bioinspiration and Biomimetics for Dental Materials11.1 Introduction11.2 Materials Dentistry: A World of Surfaces and Interfaces11.3 Bactericidal and Antibacterial Surfaces11.3.1 Controlling Oral Pathogens via Surface Structuring11.4 Cell Adhesive Surfaces Using Nanotopography11.5 Tissue Adhesive Surfaces11.6 Surfaces for Cell Proliferation and Differentiation11.7 ConclusionChapter 12 Feeder Cell Sources and Feeder-Free Methods for Human iPS Cell Culture12.1 Introduction12.2 Feeder Cells for ESC/iPSC Culture12.2.1 Mouse-Derived Feeder Cells12.2.2 Human-Derived Feeder Cells12.3 Feeder-Free Methods for ESC/iPSC Culture12.3.1 ECM-Related Materials12.3.2 Synthetic Materials12.4 ConclusionsChapter 13 Hydrogel-Based Biomimetic Environment for In Vitro Cell and Tissue Manipulation13.1 Introduction13.2 Cell and Matrix Patterning Using Hydrogel with Static Mechanical Stimulation13.3 Three-Dimensional Patterning of Mineralized Cell Groups in Hydrogel13.4 Microvessel Patterning Using Fibrin Gel with Dynamic Mechanical Stimulation13.5 ConclusionChapter 14 Trends in Periodontal Regeneration Therapy: Potential Therapeutic Strategy of Extracellular Matrix Administration for Periodontal Ligament Regeneration14.1 Introduction14.2 Periodontal Ligament Development14.2.1 Developmental Process of Dental Follicle14.2.2 Tendon/Ligament Related Molecules Involved in DF Development14.3 Microfibril is Essential for PDL Maintenance and Formation14.3.1 Fibrillin-1 Regulate PDL Formation and Maintenance14.3.2 Strategy of MFS Treatment14.4 Novel Approaches to Periodontal Tissue Regeneration Using ECM Administration Therapy14.4.1 ADAMTSL6β Serves as a Novel Molecules that Regulate Microfibril Assembly14.4.2 ADAMTSL6β Regulates Microfibril Assembly14.4.3 ADAMTSL6β Involved in PDL Formation and Repair14.5 ConclusionPart V Poster Presentation Award WinnersChapter 15 Histochemical Characteristics of Glycoproteins During Rat Palatine Gland Development15.1 Introduction15.2 Palatine Gland During Developmental Differentiation and Maturation15.2.1 Prenatal Stage15.2.2 Suckling Stage15.2.3 Transitional Stage15.2.4 Weaning Stage15.2.5 Adult Stage15.3 ConclusionsChapter 16 The Role of NFIC in Regulating Odontoblastic Differentiation of Human Molar Stem Cells from Apical Papilla16.1 Introduction16.2 Materials and Methods16.2.1 Ethical Approval of the Study Protocol and Acquisition of Samples16.2.2 Cell Culture and Induction of Mineralization16.2.3 Transplantation16.2.4 Immunohistochemical Staining and Immunocytochemistry16.2.5 RT-PCR Analysis16.2.6 Western Blotting16.3 Results16.3.1 NFIC Expression in Tooth Tissue16.3.2 NFIC Expression in hSCAPs Transplantation16.3.3 The Expression of NFIC and Odontogenic Related Genes During Osteogenic Differentiation of hSCAPs16.4 DiscussionChapter 17 Microbicidal Activity of Artificially Generated Hydroxyl Radicals17.1 Introduction17.2 Application of Hydroxyl Radicals to Disinfection Treatment17.2.1 Photolysis of H2O217.2.2 Sonolysis of Water17.2.3 Other Hydroxyl Radical Generation Systems17.3 SummaryChapter 18 High Levels of Saturated Fatty Acids may Exacerbate the Pathogenesis of Primary Sjo¨gren's Syndrome18.1 Introduction18.2 Materials and Methods18.2.1 Reagents18.2.2 Antibodies18.2.3 Cells and Cell Culture18.2.4 RNA Isolation and RT-PCR18.2.5 Measurement of IL-6 Production18.2.6 Immunoblotting18.2.7 Oil Red O Staining18.2.8 Cell Viability Assay18.2.9 Annexin V-FITC/Propidium Iodide (PI) Staining18.2.10 DAPI Staining18.2.11 Data Analysis18.3 Results and DiscussionChapter 19 Effects of Carbon Addition on Mechanical Properties and Microstructures of Ni-Free Co–Cr–W-Based Dental Alloys19.1 Introduction19.2 Effects of Carbon on Microstructural Evolution19.2.1 Phase Diagram of Co–28Cr–9W–1Si–C System19.2.2 Refinement of Solidification Microstructures by Carbon Addition [10]19.2.3 Effect of Hot-Deformation Processing on Microstructures [12]19.3 Effect of Carbon Concentration on Tensile Properties [11, 12]19.4 ConclusionsChapter 20 Periodontal Disease as a Possible Risk Factor for Alzheimer's Disease20.1 Introduction20.2 Current Status of AD in Japan20.3 Inflammation and AD20.4 Periodontal Disease and AD20.5 ConclusionChapter 21 Measurement of Skin Elasticity Using High Frequency Ultrasound Elastography21.1 Introduction21.2 Method21.2.1 Data Acquisition Setup21.2.2 Subject21.2.3 Velocity Measurement21.2.4 Shear Wave Measurement21.3 Results21.3.1 Measurement of Deformation21.3.2 Estimated Shear Wave Velocity21.4 Discussion21.5 ConclusionPart VI Poster PresentersChapter 22 Effect of Macrophage Colony-Stimulating Factor Receptor c-Fms Antibody on Lipopolysaccharide-Induced Pathological Osteoclastogenesis and Bone Resorption22.1 Biological Effect of Macrophage Colony-Stimulating Factor (M-CSF)22.2 The Role of M-CSF in Osteoclast Formation and Bone Remodeling22.3 Biological Antibody Therapy for Bone Disease22.4 The Inhibitory Effect of the Anti-c-Fms Antibody in Pathological Osteoclast Formation and Bone Resorption22.5 ConclusionsChapter 23 The Role of Th1 Cytokines on Mechanical Loading-Induced Osteoclastogenesis23.1 Osteoclast Differentiation23.2 TNF-α-Mediated Osteoclast Formation23.3 Mechanical Force Loading-Induced Osteoclast Formation and Bone Resorption23.4 Effect of Interleukin (IL)-12 on Osteoclast Formation23.5 Effect of IFN-γ on Osteoclast Formation and Bone Resorption23.6 ConclusionsChapter 24 The Ventral Primary Somatosensory Cortex of the Primate Brain: Innate Neural Interface for Dexterous Orofacial Motor Control24.1 Introduction24.2 Representation of Orofacial Structures in Area 3b24.3 Neuronal Receptive Fields (RFs) as an Indicator of Hierarchical Information Processing in the vSI24.4 Hand-Mouth Motor Coordination in Self-Feeding Behavior24.5 Temporal Analysis of Spiking Activities in Neuronal Populations and Individual NeuronsChapter 25 Possible Roles of IL-33 in Periodontal Diseases: Porphyromonas gingivalis Induced IL-33 in Human Gingival Epithelial Cells25.1 Introduction25.2 Expression of IL-33 in Periodontal Tissues from Chronic Periodontitis Patients25.3 Possible Induction of IL-33 by Gingipains from P. gingivalis in Gingival Epithelial Cells25.3.1 P. gingivalis Induces IL-33 mRNA Expression in Human Gingival Epithelial Cells in Culture25.3.2 Involvement of Gingipains in the Induction of IL-33 mRNA Expression in Human Gingival Epithelial Cells by P. gingivalis25.4 PAR-2-p38/NF-κB-Mediated Signals in IL-33 Induction25.4.1 Role of PAR-2 in the Induction of IL-33 by Gingipains25.4.2 Involvement of PLC in the Induction of IL-33 by Gingipains25.4.3 Involvement of p38 and NF-κB in the Induction of IL-33 by Gingipains25.5 Future Prospects: Possible Roles of IL-33 in Gingival Epithelial Cells in Chronic PeriodontitisChapter 26 Prospects for Liposome-Encapsulated Nisin in the Prevention of Dental Caries26.1 Introduction26.2 Cariogenic Microorganisms and Dental Caries26.3 Nisin as a Tool for Preventive Medicine26.4 Nisin Against Cariogenic Streptococci26.5 Liposomes as a Tool for Preventive Medicine26.6 Characteristics of Liposomes26.7 Characteristics of Liposome-Encapsulated Nisin26.8 Liposome-Encapsulated Nisin as a Preventive Agent for Oral and Dental Health26.9 Prospects for Liposome-Encapsulated NisinChapter 27 Clinical Chipping of Zirconia All-Ceramic Restorations27.1 Introduction27.2 Clinical Performance of Zirconia All-Ceramic Restorations27.3 Influence of Frame Thickness and Porcelain Firing Schedules27.4 Prevention of Porcelain Chipping27.5 ConclusionsChapter 28 Dentin Hypersensitivity: Etiology, Prevalence and Treatment Modalities28.1 Dentin Hypersensitivity28.1.1 Definition28.1.2 Diagnosis28.1.3 Physiology28.1.4 Mechanism of Action28.1.5 Etiology28.1.6 Prevalence28.1.7 Treatment28.1.8 Permeability28.1.9 Clinical Trials28.1.10 New Approach28.2 ConclusionChapter 29 Preventing Aspiration Pneumonia Among the Elderly: A Review Focused on the Impact of the Consistency of Food Substances29.1 Pneumonia and its Causes in the Elderly29.2 Risk Factor Cause of Aspiration Pneumonia29.3 Interventions Aimed at Preventing Aspiration Pneumonia29.3.1 Overview of Interventions29.3.2 Oral Hygiene29.3.3 Dietary Intervention29.3.4 Swallowing Therapy29.3.5 Controlling Gastroesophageal Reflux29.3.6 Improvement of Nutrition29.3.7 Enteral Tube Feeding29.3.8 Pharmacologic Therapies29.4 Benefits of Oral Ingestion29.5 Food Modification and Pneumonia29.5.1 Ways of Food Modification29.5.2 A Review of Food Modification and Pneumonia29.6 Impact of the Consistency of Food Substances on Aspiration Pneumonia29.6.1 A Prompt Report from our Study29.6.2 Advantage of Mastication of Food29.6.3 QOL29.6.4 Consideration of Modified-Texture Foods for the Elderly29.7 What Further Research Needs to be Done?
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